I at least need room for a decent GPU, so I'm stuck with a tower at the moment. But the HDDs all go into a NAS.I havent used a tower in my home in 15 years. Unless you need to fill it with HDDs for storage or need a super large monitor there is no reason. I have a NAS to take care of all that storage now. You can get laptops now that easily compete with most tower designs with respect to performance. I did use a small tower for work before i retired, but that was just because i did a lot with solidworks and needed the 2 big monitors. Those days are gone for me.
I am definitely thinking about getting another NUC and cloning the SSD from my Official QuadraphonicQuad Media Player™.